The Science
Built on published data.
Not marketing.
How eight actives reach eight different depths from one nightly pump. Every mechanism on this page links to its peer-reviewed source. Read the papers. Verify us.
Sources cited inline below. Tap any molecule in the depth map for the study behind it.
THE MECHANISM
Delivery science
The biological problem: signal noise.
The engineered solution: precision vector delivery.
8 actives at clinical dose should overwhelm your skin. Here's the engineering that prevents it.
Standard multi active cream
High signal noise
All actives release simultaneously. Receptors jam.
Standard multi active formulations dump every ingredient onto the skin surface at once. Active compounds compete for the same cellular binding sites, creating receptor saturation. The biological response is either muted entirely or triggers localised inflammation as the lipid barrier becomes overwhelmed. Expensive ingredients rendered functionally inert.
Vector ONE. Precision encapsulated delivery
Signal noise eliminated
Staggered depth. Timed release. Zero receptor competition.
Vector ONE encapsulates each active within lipid spheres and polymer matrices engineered to release at different temporal intervals and dermal depths. Surface soothing agents deploy immediately. Peptides and antioxidants bypass the epidermis over 2–4 hours. Encapsulated retinol finally reaches its target at hour 8. Pathways engaged sequentially. Barrier preserved entirely.
The 12-hour release sequence
What happens in your skin while you sleep
Hour 0–1
Surface · Immediate release
Barrier sealed. Irritation neutralised.
Unencapsulated soothing agents deploy on contact. Skin is calmed before any potent actives reach the receptors.
Hour 2–4
Epidermis · Delayed release
Peptides and antioxidants engage.
First encapsulation layer dissolves. Argireline relaxes expression lines. Vitamin C begins collagen bonding.
Argireline ~5%
Vitamin C 6%
Hour 4–8
Deep dermis · Deep penetration
Collagen synthesis activated.
Second polymer matrix releases. Tripeptide-1 triggers new collagen. Tetrapeptide-7 suppresses the inflammation that would break it down.
Tripeptide-1 ~3%
Tetrapeptide-7 ~2%
Hour 8–12
Deep dermis · Final depth activation
Retinol activates at depth.
Final lipid sphere dissolves. Encapsulated retinol reaches deep dermal receptors hours after surface agents have already calmed the barrier. No irritation. No purge.
Retinol 0.3%
Sequential receptor engagement across 4 dermal depth zones over 12 hours · Zero simultaneous binding site competition · Lipid barrier preserved from hour 0 to hour 12
DEPTH MAP
Vector-Controlled Delivery System
Eight clinical-dose actives. Three peptides.
Zero barrier compromise.
Drag to simulate how each active reaches its target depth. Tap any molecule for the peer-reviewed evidence.
Stratum Corneum
Viable Epidermis
Dermis
0μm
20μm
130μm
400μm
Shea Butter ~0.5%
Sodium PCA ~0.2%
5% Argireline
Squalane ~0.5%
H. Lecithin ~0.4%
Phytosterols ~0.2%
Sacch. Isomerate ~0.15%
Tea Extract ~0.08%
Tocopherol ~0.1%
Na Hyaluronate ~0.2%
4% Glycerin
7% Niacinamide
Panthenol ~0.4%
Centella ~0.1%
0.3% Retinol
Allantoin ~0.1%
Bisabolol ~0.1%
Licorice ~0.08%
7% Niacinamide →
8% PAD
6% Vitamin C
6% Vitamin C →
0μm
0/22 actives revealed
↕ Drag to penetrate
Surface
Deep
Layer 01. Stratum Corneum
0 – 20 μm · Dead-cell lipid matrix
Barrier Fortification + Active Reservoir
Niacinamide 7% increases ceramide synthesis 4.1–5.5× (Tanno 2000). Glycerin 4% forms a 6+ day reservoir. Argireline ~5% deposits here: 99.77% at/above SC (Kraeling 2015). Saccharide Isomerate bonds keratin for 72h hydration.
Layer 02. Viable Epidermis
20 – 130 μm · Keratinocytes + melanocytes
Multi-Target Active Release
PAD 8% reaches melanocytes for tyrosinase inhibition (Maramaldi 2002). Vitamin C 6%: 35.6% epidermal retention (Folle 2024). Niacinamide 7% suppresses melanosome transfer (Hakozaki 2002). Retinol 0.3% nano-releases at junction (Jun 2021). Bisabolol enhances permeation 17×.
Layer 03. Dermis
130 – 400 μm · Fibroblast collagen matrix
Deep Collagen Signal Delivery
Pal. Tripeptide-1 ~3%. Palmitoylation ↑ diffusivity 2.7×, activates TGF-β → collagen + GAG (CIR 2012). +4% skin thickness in 4 weeks. Vitamin C 6%. 18.4% dermis retention, COL-I ↑1,078% (Folle 2024). Only two actives with peer-reviewed dermal evidence. Both at clinical dose.
Synergy matrix
Stronger together than apart.
These actives don't just coexist. They amplify each other. Tap any pair.
17× permeation boost
SC lipid disruption drives niacinamide deeper into viable epidermis
Dual melanin pathway block
Tyrosinase inhibition + melanosome transfer suppression simultaneously
Dual collagen pathway
TGF-β signaling + direct COL-I cofactor. Two routes to the same fibroblast
Zero-irritation shield
IL-6 suppression prevents inflammation at the active release site
Mutual protection
Triple hydration lock
Reservoir + atmospheric draw + keratin bond. Three mechanisms, one barrier
×
FORMULATION
Formulation data
The Clinical Dosing Matrix.
No proprietary blends. No hidden ratios. Every active ingredient and its concentration, published. Tap any row for the published data behind the dose.
Active compound
Conc.
PAD — redness, texture, tone
8%
95%
redness cleared in published ingredient studies. 56% less burning and sensitivity. Gentler than pure azelaic acid. The same published results without the irritation that makes people quit.
Published data · redness 6 weeks · sensitivity 12 weeks
Vitamin B3 — barrier, oil control, tone
7%
62%
less melasma in published 8-week ingredient data. Controls oil without stripping. Evens skin tone and inhibits the melanin transfer behind dark spots.
Published data · 8 weeks
Stabilised Vitamin C — firmness, brightening
6%
20%
firmer skin in published 28-day data. 52% less melanin at 16 weeks. Won't oxidise in the bottle like pure L-ascorbic acid. Stays potent from first pump to last.
Published data · firmness 28d · melanin 16 weeks
Acetyl Hexapeptide-8 5% · Tripeptide-1 3% · Tetrapeptide-7 2% — quoted as supplied
10%
30–48%
less expression-line depth for Argireline in published 30-day data. Tripeptide-1 and Tetrapeptide-7 pair for collagen: 23% flatter wrinkle volume and 45% less deep-wrinkle area at 56 days. One relaxes, one builds, one protects.
Published data · 30–56 days · % as supplied
Humectant — deep hydration matrix
4%
85%
visible barrier repair in published 30-day data. Pulls moisture deep into the skin and holds it there. The foundation that makes every other active absorb and work properly.
Published data · 30 days
Time-released lipid capsule — wrinkles, pigmentation
0.3%
44%
fewer wrinkles and 84% less pigmentation in published 12-month data. Encapsulated for slow release. Strong enough to restructure, gentle enough for every night.
Published data · 12 months
Total active load
35.3%
Full INCI published · Peptide complex quoted as supplied · Stats are published ingredient data · Airless pump · 100 ml
PACKAGING
Packaging science
100% volume. Zero oxidation. The physics of the airless pump.
Every ml you pay for is every ml you get.
Scroll to dispense ↓
100% true volume
Internal cavity matches casing. No thick plastic false bottoms. 100 ml is exactly 100 ml.
Vacuum piston
Rises via negative pressure as product dispenses. Zero cream trapped on walls. 100% dispensed.
100 ml
True volume
0% air
Vacuum sealed
0% waste
Piston empties all
0 touch
No contamination
✕
Bacterial contamination
Fingers breed bacteria. Preservatives fail before the jar empties.
✕
Physical waste
Jars trap up to 10% in walls. You pay for 100, use 90.
Airless vacuum dispensing · Hermetic UV/oxygen seal · 100% volumetric yield · Zero-contact delivery
The last word
90 nights to prove it.
Or every euro back.
One bottle. One pump before bed. A quarter of a year of clinical doses. If your mirror does not show the difference, we refund everything and you keep the bottle.
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