The Science

Built on published data.
Not marketing.

The clinical and lab evidence behind one night cream: how seven actives reach eight different depths from a single nightly application. Every mechanism on this page links to its peer-reviewed source. Read the papers. Verify us.

35.3%Working ingredients
7Actives, doses printed
3Collagen peptides
14Barrier co-actives

Sources cited inline below. Tap any molecule in the depth map for the study behind it.

THE MECHANISM

Delivery science

The biological problem: signal noise.

The engineered solution: precision vector delivery.

Seven actives at label doses should overwhelm your skin. Here's the engineering that prevents it.

Standard multi active cream
High signal noise
EPIDERMIS RECEPTOR LAYER ✕ RECEPTOR SATURATION MUTED BIOLOGICAL RESPONSE
All actives release simultaneously. Receptors jam.
Standard multi active formulations dump every ingredient onto the skin surface at once. Active compounds compete for the same cellular binding sites, creating receptor saturation. The biological response is either muted entirely or triggers localised inflammation as the lipid barrier becomes overwhelmed. Expensive ingredients rendered functionally inert.
Vector ONE. Precision encapsulated delivery
Signal noise eliminated
SURFACE. IMMEDIATE MID DERMIS. 2-4 HOURS DEEP DERMIS. 8-12 HOURS BARRIER · HYDRATION · SOOTHING PEPTIDES · VITAMIN C · ARGIRELINE ENCAPSULATED RETINOL. SLOW DRIP
Staggered depth. Timed release. Zero receptor competition.
Vector ONE encapsulates each active within lipid spheres and polymer matrices engineered to release at different times and skin depths. Surface soothing agents deploy immediately. Peptides and antioxidants bypass the epidermis over 2-4 hours. Encapsulated retinol finally reaches its target at hour 8. Pathways engaged sequentially. Barrier protected, not stripped.
The 12-hour release sequence
What happens in your skin while you sleep
Hour 0–1
Surface · Immediate release
Barrier sealed. Soothing agents go first.
Unencapsulated soothing agents deploy on contact. They lay down a soothing cast before the potent actives reach the receptors.
Glycerin 4% Niacinamide 7% PAD 8%
Hour 2–4
Epidermis · Delayed release
Peptides and antioxidants engage.
First encapsulation layer dissolves. Argireline relaxes expression lines. Vitamin C begins collagen bonding.
Argireline ~5% Vitamin C 6%
Hour 4–8
Deep dermis · Peptide release
Collagen synthesis activated.
Second polymer matrix releases. Tripeptide-1 triggers new collagen. Tetrapeptide-7 suppresses the inflammation that would break it down.
Tripeptide-1 ~3% Tetrapeptide-7 ~2%
Hour 8–12
Deep dermis · Final depth activation
Retinol activates at depth.
Final lipid sphere dissolves. Encapsulated retinol reaches deep dermal receptors hours after surface agents have already calmed the barrier. A gentler ramp-up than raw retinol.
Retinol 0.3%
Sequential receptor engagement across 4 dermal depth zones over 12 hours · Zero simultaneous binding site competition · Lipid barrier preserved from hour 0 to hour 12

DEPTH MAP

Vector-Controlled Delivery System

Seven actives, every dose printed. Three peptides.
One controlled release.

Drag to simulate how each active reaches its target depth. Tap any molecule for the peer-reviewed evidence.

Stratum Corneum
Viable Epidermis
Dermis
0μm
20μm
130μm
400μm
Shea Butter ~0.5%
Sodium PCA ~0.2%
5% Argireline
Squalane ~0.5%
H. Lecithin ~0.4%
Phytosterols ~0.2%
Sacch. Isomerate ~0.15%
Tea Extract ~0.08%
Tocopherol ~0.1%
Na Hyaluronate ~0.2%
4% Glycerin
7% Niacinamide
Panthenol ~0.4%
Centella ~0.1%
0.3% Retinol
Allantoin ~0.1%
Bisabolol ~0.1%
Licorice ~0.08%
7% Niacinamide →
8% PAD
6% Vitamin C
2% Pal. Tetrapeptide-7
6% Vitamin C →
3% Pal. Tripeptide-1
0μm
0/22 ingredients revealed
↕ Drag to penetrate
Surface
Deep
Layer 01. Stratum Corneum
0 – 20 μm · Dead-cell lipid matrix
Barrier Fortification + Active Reservoir
Niacinamide 7%: ceramide levels measured 4.1–5.5× higher in the cited lab study (Tanno 2000). Glycerin 4%, the disclosed hydration base, forms a 6+ day reservoir. Argireline ~5% stays here: 99.77% at or above the stratum corneum (Kraeling 2015). Saccharide Isomerate bonds to keratin for 72h hydration.
7% Niacinamide5% Argireline4% Glycerin SqualaneSheaLecithinNa HAPhytosterolsNa PCASacch. Iso.TocopherolEGCG
Layer 02. Viable Epidermis
20 – 130 μm · Keratinocytes + melanocytes
Where the Strongest Actives Land
PAD 8% reaches the base of the epidermis (Maramaldi 2002). Vitamin C 6%: 35.6% epidermal retention (Folle 2024). Niacinamide 7% carries through this layer, with published evenness data behind it (Hakozaki 2002). Retinol 0.3% leaves its capsule at the junction (Jun 2021). Bisabolol helps the rest travel: up to 17× in published testing.
8% PAD7% Niacinamide →6% Vitamin C2% PT-70.3% Retinol PanthenolBisabololCentellaAllantoinLicorice
Layer 03. Dermis
130 – 400 μm · Fibroblast collagen matrix
The Deepest Measured Reach
Pal. Tripeptide-1 ~3%. The palmitoyl tail carries it through the surface layer 2.7× faster; skin measured 4% thicker across the four-week study (CIR 2012). Vitamin C 6%. 18.4% dermal retention, with collagen output measured 1,078% higher in the cited lab work (Folle 2024). The only two ingredients here with peer-reviewed dermal evidence. Both at the dose printed on the label.
3% Pal. Tripeptide-16% Vitamin C →
Synergy matrix
Stronger together than apart.
These actives don't just coexist. They amplify each other. Tap any pair.
Bisabolol×Niacinamide
Helps niacinamide travel
Loosening the surface lipids lets niacinamide travel further in instead of pooling on top
PAD×Niacinamide
Even tone, two ways
Two ingredients with separate published evenness data, working at different depths
PT-1×Vitamin C
Two collagen routes
The only two ingredients here with published evidence of reaching the dermis, each with its own collagen data
PT-7×All actives
Balances the actives
Keeps a strong formula comfortable as the actives are released
Vitamin C×Retinol
Mutual protection
Antioxidant cover for retinol. In published work, skin also takes up more vitamin C when retinol is present
Glycerin×HA×Sacch. Iso.
Triple hydration lock
Reservoir + atmospheric draw + keratin bond. Three mechanisms, one barrier
×

The formula

Concentration matrix

Every dose printed, every study named

Tap any compound for the published ingredient data. Full INCI, nothing hidden.

Compound
Concentration
Potassium Azeloyl Diglycinate
Brightening, oil control, redness
8%
95%
look of redness reduced in published ingredient studies. The gentler form of azelaic acid, and easy to keep using every night. Brightens, evens the look of tone and helps manage oil. The lead active in the formula.
Ingredient study · over 6 weeks
Niacinamide
Vitamin B3, barrier, oil control, tone
7%
62%
more even-looking skin tone in published 8-week ingredient data. Controls oil without stripping, and softens the look of dark spots over time.
Ingredient study · over 8 weeks
3-O-Ethyl Ascorbic Acid
Stabilised Vitamin C, firmness, brightening
6%
20%
firmer-looking skin in published 28-day data. 52% brighter-looking skin in a separate 16-week study. Won't oxidise in the bottle like pure L-ascorbic acid. Stays stable from first pump to last.
Ingredient studies · firmness over 28 days · brightness over 16 weeks
Peptide Complex
Argireline 5% · Tripeptide-1 3% · Tetrapeptide-7 2% (quoted as the blend, not as pure peptide)
10%
30–48%
look of expression lines softened for Argireline in published 30-day data. Tripeptide-1 and Tetrapeptide-7 work together: 23% smoother-looking skin and 45% look of deep lines softened in the published 56-day study. Three peptides, three different jobs.
Ingredient studies · Argireline over 30 days · peptide pair over 56 days · % as the blend
Glycerin
Hydration base, not counted as an active
4%
The humectant that pulls water into the skin and holds it there, and keeps the barrier comfortable while seven actives sit on the same face. A base, not an active. So we claim nothing for it and we do not count it among the seven.
Encapsulated Retinol
Time-released lipid capsule, wrinkles, dark spots
0.3%
44%
fewer visible wrinkles and 84% look of dark spots reduced in published 12-month data. Encapsulated for slow release. Strong enough to show on the surface, gentle enough for every night.
Ingredient study · over 12 months
Total printed dose
35.3%
Full INCI published · Peptide complex quoted as the blend · Stats are published ingredient data · Airless pump · 100 ml

Durations are how long each study ran, not how long skin takes.

See Vector ONE
From early customers
See why one wins

PACKAGING

Packaging science

100% volume. Zero oxidation. The physics of the airless pump.

Every ml you pay for is every ml you get.

100 ml TRUE VOLUME NO FALSE BOTTOM
Scroll to dispense ↓
Hermetic seal
Locks out oxygen and UV light. Retinol and Vitamin C stay potent from first pump to last.
100% true volume
Internal cavity matches casing. No thick plastic false bottoms. 100 ml is exactly 100 ml.
Vacuum piston
Rises via negative pressure as product dispenses. Zero cream trapped on walls. 100% dispensed.
100 ml
True volume
0% air
Vacuum sealed
0% waste
Piston empties all
0 touch
No contamination
✕
Bacterial contamination
Fingers breed bacteria. Preservatives fail before the jar empties.
✕
Oxidative degradation
Open jars kill retinol and Vitamin C within weeks.
✕
Physical waste
Jars trap up to 10% in walls. You pay for 100, use 90.
Airless vacuum dispensing · Hermetic UV/oxygen seal · 100% volumetric yield · Zero-contact delivery

Who this is for

You don't have to become a skincare guy.

Maybe you're the shave-and-go guy who never owned a cream. The gym guy who trains everything but his face. The new dad running on five hours. The man past 40 starting from zero. Or the man with a drawer full of bottles. Different faces, same problem: every layer thins the one before it. One bottle ends the layering. Every dose printed on the label, three pumps before bed.

The last word

120 nights to decide.
Not satisfied, money back.

One bottle. Three pumps before bed. 120 nights of the doses printed on the label. Not satisfied? Keep the bottle and ask for a prompt and courteous refund. No results conditions, no photos, no forms.

The 120 nights to decide only start once the bottle is on your shelf.

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